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Standard (Evidence Strength: Grade B) Intravesical instillation of BCG is associated with efficacy only non-significantly greater than placebo in the context of potentially serious AEs with long-term follow-up data indicating no differences between BCG- and placebo-treated patients
This could explain why the lymphoid cell lines are more susceptible to polyphenol/topoisomerase II inhibitor treatment compared with the myeloid cell lines
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This is why B12 deficiency gets mistaken for burnout, depression, or just "getting older." The symptoms overlap
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